Crystallographic Study of Solvates and Solvate Hydrates of an Antibacterial Furazidin

In this study, we present a detailed crystallographic analysis of multiple solvates an antibacterial furazidin. Solvate formation furazidin was investigated by crystallizing it from pure solvents and solvent–water mixtures. Crystal structure the obtained computational calculations were used to identify main factors leading intermolecular interactions in solvate crystal structures resulting observed hydrates. Furazidin forms hydrates with having large hydrogen bond acceptor propensity donor formic acid. hydrates, incorporation water allows additional bonds results more efficient networks which is “hooking” organic solvent molecule, slightly reduces cut-off required for obtaining solvate. The all are formed molecule layers, almost structures, hydrogen-bonded furazidin, but packing each unique. contrast, bonding most nearly identical.